Examples of polypeptides include endorphin, interferon (α-type, β-type, γ-type), interleukin, tuftsin, thymopoietin, thymosin, thymostimulin, thymic humoral factor (THF), serum thymic factor and derivatives thereof, tumor necrosis factor, colony stimulating factor (CSF), motilin, dynorphin, bombesin, neurotensin, bradykinin, caerulein, urokinase, asparaginase, kallikrein, substance P, nerve growth factor, blood coagulation factor VIII and IX, lysozyme, polymyxin B, colistin, gramicidin, bacitracin, protein synthesis-stimulating peptide, vasoactive intestinal polypeptide, platelet-derived growth factor, growth hormone- releasing factor, bone morphogenetic protein, epidermal growth factor, and erythropoietin.
Exemplos de polipeptídeos incluem a endorfina, interferon (tipo α, tipo β, tipo γ), interleucina, tuftsina, timopoietina, timosina, timostimulina, fator humoral tímico (THF), fator tímico sérico e seus derivados, fator de necrose tumoral, fator estimulante de colônias (CSF), motilina, denorfina, bombesina, neurotensina, bradiquinina, caeruleína, uroquinase, asparaginase, calicreína, substância P, fator de crescimento nervoso, fator de coagulação sanguínea VIII e IX, lisozima, polimixina B, colistina, gramicidina, bacitracina, peptídeo estimulante da síntese protéica, polipeptídio intestinal vasoativo, fator de crescimento derivado de plaquetas, fator de liberação do hormônio do crescimento, proteína morfogenética óssea, fator de crescimento epidérmico e eritropoietina.
Non-limiting examples of protein drugs capable of being conjugated to the immunoglobulin Fc fragment of the present invention include human growth hormone, bone morphogenetic protein-1 (BMP-1), growth hormone releasing hormone, growth hormone releasing peptide, interferons and interferon receptors (for example, interferon-α, -β and -γ, water-soluble type I interferon receptor, etc.), granulocyte colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor (GM-CSF), glucagon-like peptides (for example, GLP-1, etc.), G-protein-coupled receptor, interleukins (for example, interleukin-1, -2, -3, -4, -5, -6, -7, -8, -9, -10, -11, -12, -13, -14, -15, -16, -17, -18, -19, -20, -21, -22, -23, -24, -25, -26, -27, -28, -29, -30, etc.) and interleukin receptors (for example, IL-1 receptor, IL-4 receptor, etc.), enzymes (for example, glucocerebrosidase, iduronate-2-sulfatase, alpha-galactosidase-A, agalsidase alpha and beta, alpha-L-iduronidase, butyrylcholinesterase, chitinase, glutamate decarboxylase, imiglucerase, lipase, uricase, platelet-activating factor acetylhydrolase, neutral endopeptidase, myeloperoxidase, etc.), interleukin and cytokine binding proteins (for example, IL-18bp, TNF-binding protein, etc.), macrophage activating factor, macrophage peptide, B cell factor, T cell factor, protein A, allergy inhibitor, cell necrosis glycoproteins, immunotoxin, lymphotoxin, tumor necrosis factor, tumor suppressors, metastasis growth factor, alpha-1 antitrypsin, albumin, alpha-lactalbumin, apolipoprotein-E, erythropoietin, highly glycosylated erythropoietin, angiopoietins; hemoglobin, thrombin, thrombin receptor activating peptide, thrombomodulin, factor VII, factor VIIa, factor VIII, factor IX, factor XIII, plasminogen activating factor, fibrin-binding peptide, urokinase, streptokinase, hirudin, protein C, C-reactive protein, renin inhibitor, collagenase inhibitor, superoxide dismutase, leptin, platelet-derived growth factor, epithelial growth factor, epidermal growth factor, angiostatin, angiotensin, bone growth factor, bone stimulating protein, calcitonin, insulin, atriopeptin, cartilage inducing factor, elcatonin, connective tissue activating factor, tissue factor pathway inhibitor, follicle stimulating hormone, luteinizing hormone, luteinizing hormone releasing hormone, nerve growth factors (for example, nerve growth factor, ciliary neurotrophic factor, axogenesis factor-1, brain-natriuretic peptide, glial derived neurotrophic factor, netrin, neurophil inhibitor factor, neurotrophic factor, neuturin, etc.), parathyroid hormone, relaxin, secretin, somatomedin, insulin-like growth factor, adrenocortical hormone, glucagon, cholecystokinin, pancreatic polypeptide, gastrin releasing peptide, corticotropin releasing factor, thyroid stimulating hormone, autotaxin, lactoferrin, myostatin, receptors (for example, TNFR(P75), TNFR(P55), IL-1 receptor, VEGF receptor, B cell activating factor receptor, etc.), receptor antagonists (for example, IL1-Ra etc.), cell surface antigens (for example, CD 2, 3, 4, 5, 7, 11a, 11b, 18, 19, 20, 23, 25, 33, 38, 40, 45, 69, etc.), virus vaccine antigens, monoclonal antibodies, polyclonal antibodies, antibody fragments (for example, scFv, Fab, Fab', F(ab')2 and Fd), and virus derived vaccine antigens.
Exemplos não restritivos de fármacos protéicos capazes de serem conjugados ao fragmento Fc da imunoglobulina da presente invenção incluem o hormônio do crescimento humano, proteína morfogenética óssea-1 (BMP-1), hormônio de liberação do hormônio de crescimento, peptídeo de liberação do hormônio de crescimento, interferóns e receptores de interferón (por exemplo, interferón-α, -β e -γ, receptor interferón hidrossolúvel tipo I, etc.), fator estimulador de colônias de granulócitos (G-CSF), fator estimulador de colônias de granulócitos-macrófagos (GM-CSF), peptídeos do tipo glucágono (por exemplo, GLP-1, etc.), receptor acoplado à proteína G, interleucinas (por exemplo, interleucina-1, -2, -3, -4, -5, -6, -7, -8, -9, -10, -11, -12, -13, -14, -15, -16, -17, -18, -19, -20, -21, -22, -23, -24, -25, -26, -27, -28, -29, -30, etc.) e receptores de interleucina (por exemplo, receptor de IL-1, receptor de IL-4, etc.), enzimas (por exemplo, glucocerebrosidase, iduronato-2-sulfatase, alfa-galactosidase-A, agalsidase alfa e beta, alfa-L-iduronidase, butirilcolinesterase, quitinase, glutamato decarboxilase, imiglucerase, lipase, uricase, fator ativador de plaquetas, acetilhidrolase, endopeptidase neutra, mieloperoxidase, etc.), interleucina e proteínas de ligação à citocina (por exemplo, IL-18bp, proteína de ligação ao TNF, etc.), fator ativador de macrófagos, peptídeo de macrófago, fator de células B, fator de células T, proteína A, inibidor de alergia, glicoproteínas de necrose celular, imunotoxina, linfotoxina, fator de necrose tumoral, supressores tumorais, fator de crescimento da metástaste, antitripsina alfa-1, albumina, alfa-lactalbumina, apolipoproteína-E, eritropoietina, eritropoietina altamente glicosilada, angiopoietinas; hemoglobina, trombina, peptídeo de ativação do receptor da trombina, trombomodulina, fator VII, fator VIIa, fator VIII, fator IX, fator XIII, fator ativador de plasminógeno, peptídeo de ligação à fibrina, uroquinase, estreptoquinase, hirudina, proteína C, proteína C-reativa, inibidor da renina, inibidor da colagenase, superóxido dismutase, leptina, fator de crescimento derivado de plaquetas, fator de crescimento epitelial, fator de crescimento epidérmico, angiostatina, angiotensina, fator de crescimento ósseo, proteína de estimulação óssea, calcitonina, insulina, atriopeptina, fator de indução de cartilagem, elcatonina, fator ativador do tecido conjuntivo, inibidor da via do fator tecidual, hormônio estimulador folicular, hormônio luteinizante, hormônio de liberação do hormônio luteinizante, fatores de crescimento nervoso (por exemplo, fator de crescimento nervoso, fator neurotrófico ciliar, fator de axogênese-1, peptídeo natriurético cerebral, fator neurotrófico derivado da glia, netrina, fator inibidor de neurófilos, fator neurotrófico, neuturina, etc.), hormônio paratireoide, relaxina, secretina, somatomedina, fator de crescimento do tipo insulina, hormônio adrenocortical, glucágono, colecistocinina, polipeptídeo pancreático, peptídeo de liberação da gastrina, fator de liberação da corticotropina, hormônio estimulador da tireoide, autotaxina, lactoferrina, miostatina, receptores (por exemplo, TNFR(P75), TNFR(P55), receptor de IL-1, receptor VEGF, receptor do fator ativador de células B, etc.), antagonistas do receptor (por exemplo, IL1-Ra etc.), antígenos da superfície celular (por exemplo, CD 2, 3, 4, 5, 7, 11a, 11b, 18, 19, 20, 23, 25, 33, 38, 40, 45, 69, etc.), antígenos da vacina de virus, anticorpos monoclonais, anticorpos policlonais, fragmentos de anticorpos (por exemplo, scFv, Fab, Fab', F(ab')2 e Fd), e antígenos de vacina derivados de virus.
Non-limiting examples of protein drugs capable of being conjugated to the immunoglobulin Fc fragment of the present invention include human growth hormone, bone morphogenetic protein-1 (BMP-1), growth hormone releasing hormone, growth hormone releasing peptide, interferons and interferon receptors (for example, interferon-α, -β and -γ, water-soluble type I interferon receptor, etc.), granulocyte colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor (GM-CSF), glucagon-like peptides (for example, GLP-1, etc.), G-protein-coupled receptor, interleukins (for example, interleukin-1, -2, -3, -4, -5, -6, -7, -8, -9, -10, -11, -12, -13, -14, -15, -16, -17, -18, -19, -20, -21, -22, -23, -24, -25, -26, -27, -28, -29, -30, etc.) and interleukin receptors (for example, IL-1 receptor, IL-4 receptor, etc.), enzymes (for example, glucocerebrosidase, iduronate-2-sulfatase, alpha-galactosidase-A, agalsidase alpha and beta, alpha-L-iduronidase, butyrylcholinesterase, chitinase, glutamate decarboxylase, imiglucerase, lipase, uricase, platelet-activating factor acetylhydrolase, neutral endopeptidase, myeloperoxidase, etc.), interleukin and cytokine binding proteins (for example, IL-18bp, TNF-binding protein, etc.), macrophage activating factor, macrophage peptide, B cell factor, T cell factor, protein A, allergy inhibitor, cell necrosis glycoproteins, immunotoxin, lymphotoxin, tumor necrosis factor, tumor suppressors, metastasis growth factor, alpha-1 antitrypsin, albumin, alpha-lactalbumin, apolipoprotein-E, erythropoietin, highly glycosylated erythropoietin, angiopoietins; hemoglobin, thrombin, thrombin receptor activating peptide, thrombomodulin, factor VII, factor VIIa, factor VIII, factor IX, factor XIII, plasminogen activating factor, fibrin-binding peptide, urokinase, streptokinase, hirudin, protein C, C-reactive protein, renin inhibitor, collagenase inhibitor, superoxide dismutase, leptin, platelet-derived growth factor, epithelial growth factor, epidermal growth factor, angiostatin, angiotensin, bone growth factor, bone stimulating protein, calcitonin, insulin, atriopeptin, cartilage inducing factor, elcatonin, connective tissue activating factor, tissue factor pathway inhibitor, follicle stimulating hormone, luteinizing hormone, luteinizing hormone releasing hormone, nerve growth factors (for example, nerve growth factor, ciliary neurotrophic factor, axogenesis factor-1, brain-natriuretic peptide, glial derived neurotrophic factor, netrin, neurophil inhibitor factor, neurotrophic factor, neuturin, etc.), parathyroid hormone, relaxin, secretin, somatomedin, insulin-like growth factor, adrenocortical hormone, glucagon, cholecystokinin, pancreatic polypeptide, gastrin releasing peptide, corticotropin releasing factor, thyroid stimulating hormone, autotaxin, lactoferrin, myostatin, receptors (for example, TNFR(P75), TNFR(P55), IL-1 receptor, VEGF receptor, B cell activating factor receptor, etc.), receptor antagonists (for example, IL1-Ra etc.), cell surface antigens (for example, CD 2, 3, 4, 5, 7, 11a, 11b, 18, 19, 20, 23, 25, 33, 38, 40, 45, 69, etc.), virus vaccine antigens, monoclonal antibodies, polyclonal antibodies, antibody fragments (for example, scFv, Fab, Fab', F(ab')2 and Fd), and virus derived vaccine antigens.
Exemplos não restritivos de fármacos protéicos capazes de serem conjugados ao fragmento Fc da imunoglobulina da presente invenção incluem o hormônio do crescimento humano, proteína morfogenética óssea-1 (BMP-1), hormônio de liberação do hormônio de crescimento, peptídeo de liberação do hormônio de crescimento, interferóns e receptores de interferón (por exemplo, interferón-α, -β e -γ, receptor interferón hidrossolúvel tipo I, etc.), fator estimulador de colônias de granulócitos (G-CSF), fator estimulador de colônicas de granulócitos-macrófagos (GM-CSF), peptídeos do tipo glucágono (por exemplo, GLP-1, etc.), receptor acoplado à proteína G, interleucinas (por exemplo, interleucina-1, -2, -3, -4, -5, -6, -7, -8, -9, -10, -11, -12, -13, -14, -15, -16, -17, -18, -19, -20, -21, -22, -23, -24, -25, -26, -27, -28, -29, -30, etc.) e receptores de interleucina (por exemplo, receptor de IL-1, receptor de IL-4, etc.), enzimas (por exemplo, glucocerebrosidase, iduronato-2-sulfatase, alfa-galactosidase-A, agalsidase alfa e beta, alfa-L-iduronidase, butirilcolinesterase, quitinase, glutamato decarboxilase, imiglucerase, lipase, uricase, fator ativador de paquetas, acetilhidrolase, endopeptidase neutra, mieloperoxidase, etc.), interleucina e proteínas de ligação à citocina (por exemplo, IL-18bp, proteína de ligação ao TNF, etc.), fator ativador de macrófagos, peptídeo de macrófago, fator de células B, fator de células T, proteína A, inibidor de alergia, glicoproteínas de necrose celular, imunotoxina, linfotoxina, fator de necrose tumoral, supressores tumorais, fator de crescimento da metástaste, antitripsina alfa-1, albumina, alfa-lactalbumina, apolipoproteína-E, eritropoietina, eritropoietina altamente glicosilada, angiopoietinas; hemoglobina, trombina, peptídeo de ativação do receptor da trombina, trombomodulina, fator VII, fator VIIa, fator VIII, fator IX, fator XIII, fator ativador de plasminógeno, peptídeo de ligação à fibrina, uroquinase, estreptoquinase, hirudina, proteína C, proteína C-reativa, inibidor da renina, inibidor da colagenase, superóxido dismutase, leptina, fator de crescimento derivado de plaquetas, fator de crescimento epitelial, fator de crescimnto epidérmico, angiostatina, angiotensina, fator de crescimento ósseo, proteína de estimulação óssea, calcitonina, insulina, atriopeptina, fator de indução de cartilagem, elcatonina, fator ativador do tecido conjuntivo, inibidor da via do fator tecidual, hormônio estimulador folicular, hormônio luteinizante, hormônio de liberação do hormônio luteinizante, fatores de crescimento nervoso (por exemplo, fator de crescimento nervoso, fator neurotrófico ciliar, fator de axogênese-1, peptídeo natriurético cerebral, fator neurotrófico derivado da glia, netrina, fator inibidor de neurófilos, fator neurotrófico, neuturina, etc.), hormônio paratireoide, relaxina, secretina, somatomedina, fator de crescimento do tipo insulina, hormônio adrenocortical, glucágono, colecistocinina, polipeptídeo pancreático, peptídeo de liberação da gastrina, fator de liberação da corticotropina, hormônio estimulador da tireoide, autotaxina, lactoferrina, miostatina, receptores (por exemplo, TNFR(P75), TNFR(P55), receptor de IL-1, receptor VEGF, receptor do fator ativador de células B, etc.), antagonistas do receptor (por exemplo, IL1-Ra etc.), antígenos da superfície celular (por exemplo, CD 2, 3, 4, 5, 7, 11a, 11b, 18, 19, 20, 23, 25, 33, 38, 40, 45, 69, etc.), antígenos da vacina de virus, anticorpos monoclonais, anticorpos policlonais, fragmentos de anticorpos (por exemplo, scFv, Fab, Fab', F(ab')2 e Fd), e antígenos de vacina derivados de virus.
Non-limiting examples of protein drugs capable of being conjugated to the immunoglobulin Fc fragment of the present invention include human growth hormone, bone morphogenetic protein-1 (BMP-1), growth hormone releasing hormone, growth hormone releasing peptide, interferons and interferon receptors (for example, interferon-α, -β and -γ, water-soluble type I interferon receptor, etc.), granulocyte colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor (GM-CSF), glucagon-like peptides (for example, GLP-1, etc.), G-protein-coupled receptor, interleukins (for example, interleukin-1, -2, -3, -4, -5, -6, -7, -8, -9, -10, -11, -12, -13, -14, -15, -16, -17, -18, -19, -20, -21, -22, -23, -24, -25, -26, -27, -28, -29, -30, etc.) and interleukin receptors (for example, IL-1 receptor, IL-4 receptor, etc.), enzymes (for example, glucocerebrosidase, iduronate-2-sulfatase, alpha-galactosidase-A, agalsidase alpha and beta, alpha-L-iduronidase, butyrylcholinesterase, chitinase, glutamate decarboxylase, imiglucerase, lipase, uricase, platelet-activating factor acetylhydrolase, neutral endopeptidase, myeloperoxidase, etc.), interleukin and cytokine binding proteins (for example, IL-18bp, TNF-binding protein, etc.), macrophage activating factor, macrophage peptide, B cell factor, T cell factor, protein A, allergy inhibitor, cell necrosis glycoproteins, immunotoxin, lymphotoxin, tumor necrosis factor, tumor suppressors, metastasis growth factor, alpha-1 antitrypsin, albumin, alpha-lactalbumin, apolipoprotein-E, erythropoietin, highly glycosylated erythropoietin, angiopoietins; hemoglobin, thrombin, thrombin receptor activating peptide, thrombomodulin, factor VII, factor VIIa, factor VIII, factor IX, factor XIII, plasminogen activating factor, fibrin-binding peptide, urokinase, streptokinase, hirudin, protein C, C-reactive protein, renin inhibitor, collagenase inhibitor, superoxide dismutase, leptin, platelet-derived growth factor, epithelial growth factor, epidermal growth factor, angiostatin, angiotensin, bone growth factor, bone stimulating protein, calcitonin, insulin, atriopeptin, cartilage inducing factor, elcatonin, connective tissue activating factor, tissue factor pathway inhibitor, follicle stimulating hormone, luteinizing hormone, luteinizing hormone releasing hormone, nerve growth factors (for example, nerve growth factor, ciliary neurotrophic factor, axogenesis factor-1, brain-natriuretic peptide, glial derived neurotrophic factor, netrin, neurophil inhibitor factor, neurotrophic factor, neuturin, etc.), parathyroid hormone, relaxin, secretin, somatomedin, insulin-like growth factor, adrenocortical hormone, glucagon, cholecystokinin, pancreatic polypeptide, gastrin releasing peptide, corticotropin releasing factor, thyroid stimulating hormone, autotaxin, lactoferrin, myostatin, receptors (for example, TNFR(P75), TNFR(P55), IL-1 receptor, VEGF receptor, B cell activating factor receptor, etc.), receptor antagonists (for example, IL1-Ra etc.), cell surface antigens (for example, CD 2, 3, 4, 5, 7, 11a, 11b, 18, 19, 20, 23, 25, 33, 38, 40, 45, 69, etc.), virus vaccine antigens, monoclonal antibodies, polyclonal antibodies, antibody fragments (for example, scFv, Fab, Fab', F(ab')2 and Fd), and virus derived vaccine antigens.
Exemplos não restritivos de fármacos protéicos capazes de serem conjugados ao fragmento Fc da imunoglobulina da presente invenção incluem o hormônio do crescimento humano, proteína morfogenética óssea-1 (BMP-1), hormônio de liberação do hormônio de crescimento, peptídeo de liberação do hormônio de crescimento, interferóns e receptores de interferón (por exemplo, interferón-α, -β e -γ, receptor interferón hidrossolúvel tipo I, etc.), fator estimulador de colônias de granulócitos (G-CSF), fator estimulador de colônicas de granulócitos-macrófagos (GM-CSF), peptídeos do tipo glucágono (por exemplo, GLP-1, etc.), receptor acoplado à proteína G, interleucinas (por exemplo, interleucina-1, -2, -3, -4, -5, -6, -7, -8, -9, -10, -11, -12, -13, -14, -15, -16, -17, -18, -19, -20, -21, -22, -23, -24, -25, -26, -27, -28, -29, -30, etc.) e receptores de interleucina (por exemplo, receptor de IL-1, receptor de IL-4, etc.), enzimas (por exemplo, glucocerebrosidase, iduronato-2-sulfatase, alfa-galactosidase-A, agalsidase alfa e beta, alfa-L-iduronidase, butirilcolinesterase, quitinase, glutamato decarboxilase, imiglucerase, lipase, uricase, fator ativador de paquetas, acetilhidrolase, endopeptidase neutra, mieloperoxidase, etc.), interleucina e proteínas de ligação à citocina (por exemplo, IL-18bp, proteína de ligação ao TNF, etc.), fator ativador de macrófagos, peptídeo de macrófago, fator de células B, fator de células T, proteína A, inibidor de alergia, glicoproteínas de necrose celular, imunotoxina, linfotoxina, fator de necrose tumoral, supressores tumorais, fator de crescimento da metástaste, antitripsina alfa-1, albumina, alfa-lactalbumina, apolipoproteína-E, eritropoietina, eritropoietina altamente glicosilada, angiopoietinas; hemoglobina, trombina, peptídeo de ativação do receptor da trombina, trombomodulina, fator VII, fator VIIa, fator VIII, fator IX, fator XIII, fator ativador de plasminógeno, peptídeo de ligação à fibrina, uroquinase, estreptoquinase, hirudina, proteína C, proteína C-reativa, inibidor da renina, inibidor da colagenase, superóxido dismutase, leptina, fator de crescimento derivado de plaquetas, fator de crescimento epitelial, fator de crescimnto epidérmico, angiostatina, angiotensina, fator de crescimento ósseo, proteína de estimulação óssea, calcitonina, insulina, atriopeptina, fator de indução de cartilagem, elcatonina, fator ativador do tecido conjuntivo, inibidor da via do fator tecidual, hormônio estimulador folicular, hormônio luteinizante, hormônio de liberação do hormônio luteinizante, fatores de crescimento nervoso (por exemplo, fator de crescimento nervoso, fator neurotrófico ciliar, fator de axogênese-1, peptídeo natriurético cerebral, fator neurotrófico derivado da glia, netrina, fator inibidor de neurófilos, fator neurotrófico, neuturina, etc.), hormônio paratireoide, relaxina, secretina, somatomedina, fator de crescimento do tipo insulina, hormônio adrenocortical, glucágono, colecistocinina, polipeptídeo pancreático, peptídeo de liberação da gastrina, fator de liberação da corticotropina, hormônio estimulador da tireoide, autotaxina, lactoferrina, miostatina, receptores (por exemplo, TNFR(P75), TNFR(P55), receptor de IL-1, receptor VEGF, receptor do fator ativador de células B, etc.), antagonistas do receptor (por exemplo, IL1-Ra etc.), antígenos da superfície celular (por exemplo, CD 2, 3, 4, 5, 7, 11a, 11b, 18, 19, 20, 23, 25, 33, 38, 40, 45, 69, etc.), antígenos da vacina de virus, anticorpos monoclonais, anticorpos policlonais, fragmentos de anticorpos (por exemplo, scFv, Fab, Fab', F(ab')2 e Fd), e antígenos de vacina derivados de virus.
Examples of polypeptides include endorphin, interferon (α-type, β-type, γ-type), interleukin, tuftsin, thymopoietin, thymosin, thy- mostimulin, thymic humoral factor (THF), serum thymic factor and derivatives thereof, tumor necrosis factor, colony stimulating factor (CSF), motilin, dynorphin, bombesin, neurotensin, bradykinin, caerulein, urokinase, asparaginase, kallikrein, substance P, nerve growth factor, blood coagulation factor VIII and IX, lysozyme, polymyxin B, colistin, gramicidin, bacitracin, protein synthesis-stimulating peptide, vasoactive intestinal polypeptide, platelet-derived growth factor, growth hormone- releasing factor, bone morphogenetic protein, epidermal growth factor, and erythropoietin.
Exemplos de polipeptídeos incluem a endorfina, interferon (tipo α, tipo β, tipo γ), interleucina, tuftsina, timopoietina, timosina, timostimulina, fator humoral tímico (THF), fator tímico sérico e seus derivados, fator de necrose tumoral, fator estimulante de colônias (CSF), motilina, denorfina, bombesina, neurotensina, bradiquinina, caeruuleína, uroquinase, asparaginase, calicreína, substância P, fator de crescimento nervoso, fator de coagulação sanguinea VIII e IX, lisozima, polimixina B, colistina, gramicidina, bacitracina, peptídeo estimulante da síntese protéica, polipeptoideo intestinal vasoativo, fator de crescimento derivado de plaquetas, fator de liberação do hormônio do crescimento, proteína morfogenética óssea, fator de crescimento epidérmico e eritropoietina.
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